みさき内科リウマチ・関節炎クリニック｜スタッフ紹介-実績・著書・論文

1 Arthritis Res Ther. 2011 May 18;13(3):
Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice.
Misaki K, Morinobu A, Saegusa J, Kasagi S, Fujita M, Miyamoto Y, Matsuki F, Kumagai S.

2 Biochem Biophys Res Commun. 2013 Sep 6;438(4):778-83
CD45RA-Foxp3(high) activated/effector regulatory T cells in the CCR7+CD45RA-CD27+CD28+central memory subset are decreased in peripheral blood from patients with rheumatoid arthritis.
Matsuki F, Saegusa J, Miyamoto Y, Misaki K, Kumagai S, Morinobu A.

3. Mod Rheumatol. 2013 Jan;23(1):89-96.
Mycophenolate mofetil versus intravenous cyclophosphamide for induction treatment of proliferative lupus nephritis in a Japanese population: a retrospective study.
Onishi A, Sugiyama D, Tsuji G, Nakazawa T, Kogata Y, Tsuda K, Naka I, Nishimura K, Misaki K, Kurimoto C, Hayashi H, Kageyama G, Saegusa J, Sugimoto T, Kawano S, Kumagai S, Morinobu A.

4. Mod Rheumatol. 2011 Aug;21(4):391-6.
Role of imaging studies in the diagnosis and evaluation of giant cell arteritis in Japanese: report of eight cases.
Morinobu A, Tsuji G, Kasagi S, Saegusa J, Hayashi H, Nakazawa T, Kogata Y, Misaki K, Nishimura K, Sendo S, Miura N, Kawano S, Kumagai S.

5. BMC Pulm Med. 2015 Jul 30;15:78
Comparative investigation of respiratory tract involvement in granulomatosis with polyangiitis between PR3-ANCA positive and MPO-ANCA positive cases: a retrospective cohort study.
Ikeda S, Arita M, Misaki K, Kashiwagi Y, Ito Y, Yamada H, Hotta M, Nishiyama A, Ito A, Noyama M, Koyama T, Notohara K, Ishida T.

6. Springerplus. 2015 May 28;4:240.
Incidence and impact of interstitial lung disease and malignancy in patients with polymyositis, dermatomyositis, and clinically amyopathic dermatomyositis: a retrospective cohort study.
Ikeda S, Arita M, Misaki K, Mishima S, Takaiwa T, Nishiyama A, Ito A, Furuta K, Yokoyama T, Tokioka F, Noyama M, Yoshioka H, Ishida T.

7. Mod Rheumatol. 2015 Sep 18:1-20
Consensus-based identification of factors related to false-positives in ultrasound scanning of synovitis and tenosynovitis.
Ikeda K, Narita A, Ogasawara M, Ohno S, Kawahito Y, Kawakami A, Ito H, Matsushita I, Suzuki T, Misaki K, Ogura T, Kamishima T, Seto Y, Nakahara R, Kaneko A, Nakamura T, Henmi M, Fukae J, Nishida K, Sumida T, Koike T.

8. BMC Pulm Med. 2015 Dec 9;15(1):159.
Interstitial lung disease in clinically amyopathic dermatomyositis with and without anti-MDA-5 antibody: to lump or split?
Ikeda S, Arita M, Morita M, Ikeo S, Ito A, Tokioka F, Noyama M, Misaki K, Notohara K, Ishida T.

9. Intern Med.2019;58(4):593-601
Acute Pulmonary Hypertension Crisis after Adalimumab Reduction in Rheumatoid Vasculitis.
Yamasaki G, Okano M, Nakayama K, Jimbo N, Sendo S, Tamada N, Misaki K, Shinkura Y, Yanaka K, Tanaka H, Akashi K, Morinobu A, Yokozaki H, Emoto N, Hirata KI.

10. Pharmacogenomics J. 2020 Jun;20(3):433-442.
Genetic and clinical prediction models for the efficacy and hepatotoxicity of methotrexate in patients with rheumatoid arthritis: a multicenter cohort study.
Onishi A, Kamitsuji S, Nishida M, Uemura Y, Takahashi M, Saito T, Yoshida Y, Kobayashi M, Kawate M, Nishimura K, Misaki K, Nobuhara Y, Nakazawa T, Hatachi S, Tsuji G, Morinobu A, Kumagai S.

11. Rheumatol Int. 2020 Jul;40(7):1101-1109.
Shoulder ultrasound and serum lactate dehydrogenase predict inadequate response to glucocorticoid treatment in patients with polymyalgia rheumatica.
Ayano M, Arinobu Y, Tsukamoto H, Ota SI, Misaki K, Nishimura K, Kimoto Y, Mitoma H, Akahoshi M, Akashi K, Horiuchi T, Niiro H.

12. Modern Rheumatology 2022 Aug 20;32(5):846-856
Effectiveness and Safety of Subcutaneous Abatacept in Biologic-Naïve RA Patients at Week 52: A Japanese Multicenter Investigational Study (ORIGAMI Study)
Naoto Tamura, Takanori Azuma, Kenta Misaki, Rei Yamaguchi, Fuminori Hirano, Eiji Sugiyama, Daisuke Kanai, Yohko Murakawa, Motohiro Oribe, Takahito Kimata, Kazutoshi Aoki, Tomoko Sugiura, Koji Takasugi, Yuya Takakubo, Yasuyuki Tomita, Takeo Isozaki, Toshihiro Nanki, Naooki Katsuyama, Takanori Kuroiwa, Hideto Oshikawa, Motohide Kaneko, Hiroshi Fujinaga, Kiwamu Saito, Eiichi Tanaka, Eisuke Inoue, Yuri Yoshizawa, Shigeru Matsumoto, Hisashi Yamanaka　and Masayoshi Harigai; ORIGAMI Study Group

１３．Modern Rheumatology 2023 Mar 2;33(2):271-278
Influence of concomitant methotrexate use on the clinical effectiveness, retention, and safety of abatacept in biologic-naïve patients with rheumatoid arthritis: post-hoc subgroup analysis of ORIGAMI study
Takanori Azuma, Kenta Misaki, Makio Kusaoi, Yoko Suzuki, Shinji Higa, Yoshitaka Kumon, Tamami Yoshitama, Taio Naniwa, Shinsuke Yamada, Tadashi Okano, Kimihiko Takeuchi, Kei Ikeda, Kenshi Higami, Masayuki Inoo, Tetsuji Sawada, Chonte Kang, Masatoshi Hayashi, Yuko Nagaya, Takafumi Hagiwara, Eisuke Shono, Shinkichi Himeno, Eiichi Tanaka, Eisuke Inoue, Yuri Yoshizawa, Michiaki Kadode, Hisashi Yamanaka, Masayoshi Harigai

１４. Modern Rheumatol Case Rep. 2023 Jan 3;7(1):223-226.
Tietze's syndrome presenting as enthesitis diagnosed by ultrasound: a case report
Miyoshi Y, Kenta Misaki

15. Mod Rheumatol. 2023 Mar 2;33(2):271-278
Influence of Concomitant Methotrexate use on the Clinical Effectiveness, Retention, and Safety of Abatacept in Biologic-Naïve Patients with Rheumatoid Arthritis: Post-hoc Subgroup Analysis of ORIGAMI Study
Azuma T, Misaki K, Kusaoi M, Suzuki Y, Higa S, Kumon Y, Yoshitama,Naniwa T, Yamada S, Okano T, Takeuchi K, Ikeda K, Higami K, Inoo M, Sawada T, Kang C, Hayashi M, Nagaya Y, Hagiwara T, Shono E, Himeno S, Tanaka E, Inoue E, Yoshizawa Y, Kadode M, Yamanaka H, Harigai M.

16. Mod Rheumatol. 2023 May 26;road045. Online ahead of print
Associations of disease duration and anti-citrullinated peptide antibody status with the effectiveness of abatacept in biologic-naïve patients with rheumatoid arthritis: Post-hoc analysis of a multicentre, real-world observational study in Japan (ORIGAMI)
Kenta Misaki Naoto Tamura , Takanori Azuma , Koichiro Shinoda , Masao Tanaka , Hiroshi Fujiwara , Hideki Tsuboi , Tsuyoshi Kasama , Ryusuke Yoshimi , Tadamasa Hanyu , Yoshiaki Kusaka , Makoto Hirao , Makoto Onishi , Ayumi Uchino , Tomomasa Izumiyama , Kwang-Seok Yang , Noriyoshi Ogawa , Kiyoshi Matsui , Kazuhiro Kurasawa , Satoshi Kawai , Hidekata Yasuoka , Noriaki Okumura , Yo Ueda , Eiichi Tanaka , Eisuke Inoue , Katsuki Tsuritani , Shigeru Matsumoto , Hisashi Yamanaka , Masayoshi Harigai

17.Mod Rheumatol 2023 Aug 25;road082
Contribution of the factors to EuroQol 5 Dimensions in rheumatoid arthritis patients achieving low disease activity/remission with abatacept treatment: post-hoc subgroup analyses of the Japanese real-world observational study "ORIGAMI study
Masayoshi Harigai, Eiichi Tanaka, Eisuke Inoue, Naoto Tamura,
Kenta Misaki, Takanori Azuma, Shintaro Hirata, Fuminori Hirano, Yoshinori Taniguchi, Masaki Mitsuhashi, Masahiro Kondo, Motohiro Oribe, Kazutoshi Aoki, Michiaki Kadode, Katsuki Tsuritani, Hisashi Yamanaka

18．Int J Rheum Dis. 2024 Feb;27(2):e15080.
Pulmonary alveolar proteinosis during treatment of immune-mediated necrotizing myopathy.
Dobashi N, Sada KE, Kanemori G, Okada T, Tarutani Y, Yamamoto M, Yabe M, Inoue K, Imaizumi Y, Nishii M, Katsurada M, Misaki K.

19．Mod Rheumatology 2024 May 10:roae043
Factors contributing to the improvement in J-HAQ after 3 years of treatment with abatacept in biologic-naïve rheumatoid arthritis patients: Interim results of a long-term, observational, multicentre study in Japan (ORIGAMI)
Kenta Misaki , Eiichi Tanaka 2, Eisuke Inoue 2 3, Naoto Tamura 4, Fuminori Hirano 5, Yoshinori Taniguchi 6, Hiroshi Sato 7, Taio Naniwa 8, Hideto Oshikawa 9, Tamami Yoshitama 10, Yuya Takakubo 11, Yoko Suzuki 12, Shinkichi Himeno 13, Katsuki Tsuritani 14, Shigeru Matsumoto 15, Hisashi Yamanaka 2 16, Masayoshi Harigai

20．BMJ Open. 2024 Nov 17;14(11):e090668.
Optimal timing of recombinant herpes zoster virus vaccination for a JAK inhibitor treatment in rheumatoid arthritis: a multicentre, open-label, randomised comparative study (STOP-HZ study): study protocol.
Takanashi S, Ohmura K, Misaki K, Ihata A, Matsui T, Tohma S, Saegusa J, Sato S, Matsubara T, Yamaoka K, Amano K, Miyamoto T, Mori Y, Kaneko Y.

21. Arthritis Res Ther 2025 Apr 5;27(1):82
Discontinuation vs. continuation of concomitant methotrexate in patients with rheumatoid arthritis on certolizumab pegol: results from a randomised, controlled trial
Shuji Asai , Toshihisa Kojima , Hajime Ishikawa , Nobumasa Miyake , Masanari Kodera , Hisanori Hasegawa , Yasumori Sobue , Yasuhide Kanayama , Hiromi Shimada , Yuji Hirano , Toshihiko Hidaka , Takayoshi Fujibayashi , Takuya Matsumoto , Tomonori Kobayakawa , Hidekata Yasuoka , Takefumi Kato , Masahiro Hanabayashi , Yuko Kaneko , Masahiro Tada , Koichi Murata , Kenta Misaki , Masahiko Ando , Yachiyo Kuwatsuka , Mochihito Suzuki , Kenya Terabe , Shiro Imagama

22. BMJ Open. 2024 Nov 17;14(11):e090668.
Optimal timing of recombinant herpes zoster virus vaccination for a JAK inhibitor treatment in rheumatoid arthritis: a multicentre, open-label, randomised comparative study (STOP-HZ study): study protocol.
Takanashi S, Ohmura K, Misaki K, Ihata A, Matsui T, Tohma S, Saegusa J, Sato S, Matsubara T, Yamaoka K, Amano K, Miyamoto T, Mori Y, Kaneko Y.